Innovations in ADHD.

Innovations for You.

Our unique technology is designed to release your ADHD medication continuously through the day.1

Learn more about the Tris family of ADHD treatment options below.

Stimulant
ADHD Treatments

For patients 6 years and older with ADHD

Amphetamine Treatments

DYANAVEL XR Tablet amphetamine extended-release tablets 5mg, 10mg, 15mg, 20mg Logo Once Daily DYANAVEL XR extended release
Tris Once-Daily ADHD Tablet Amphetamine Tablet Icon
Once-daily tablet amphetamine
DYANAVEL XR Liquid amphetamine extended-release oral suspension 2.5 mg/mL Logo/mL Logo DYANAVEL XR extended release oral suspension
Tris Once-Daily ADHD Liquid Amphetamine Droplet Icon
Once-daily liquid amphetamine

Methylphenidate Treatments

QuilliChew ER methylphenidate HCl for extended-release chewable tablets 20mg, 30mg, 40mg Logo QuilliChew ER, the only once-daily extended-release methylphenidate tablet
Tris Once-Daily ADHD Tablet Methylphenidate Tablet Icon
Once-daily tablet methylphenidate
Quillivant XR methylphenidate HCl for extended-release oral suspension 25mg/5mL Logo Quillivant XR, the first once-daily, long-acting* liquid methylphenidate treatment
Tris Once-Daily ADHD Liquid Methylphenidate Droplet Icon
Once-daily liquid methylphenidate

Non-Stimulant
ADHD Treatment

For pediatric patients 6 years and older with ADHD

Clonidine

ONYDA XR Once-nightly liquid clonidine ONYDA XR Once-nightly liquid clonidine
Tris Once-Daily ADHD Liquid Methylphenidate Droplet Icon
Once-nightly liquid clonidine

DYANAVEL® XR (amphetamine), Quillivant XR® (methylphenidate HCI), and QuilliChew ER® (methylphenidate HCI) are central nervous system (CNS) stimulant prescription medicines used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in people 6 years and older. These medicines may help increase attention and decrease impulsiveness and hyperactivity in people with ADHD.

It is not known if DYANAVEL XR, Quillivant XR, and QuilliChew ER are safe and effective in children under 6 years of age.

DYANAVEL XR, Quillivant XR, and QuilliChew ER are federally controlled substances (CII) because they can be a target for people who abuse prescription medicines or street drugs. DYANAVEL XR, Quillivant XR, and QuilliChew ER have a high chance for abuse and misuse and may lead to substance use problems, including addiction. Keep these medicines in a safe place to prevent abuse and misuse. Selling or giving away these medicines may harm others and is against the law. See additional Important Safety Information below.

ONYDA™ XR (clonidine HCI) is a prescription medicine used for the treatment of attention deficit hyperactivity disorder (ADHD) alone or with certain other ADHD medicines in children 6 years of age and older.

It is not known if ONYDA XR is safe and effective in children under 6 years of age.

Click here for ONYDA XR Important Safey Information.

Why choose Tris ADHD medications?

Tris ADHD LiquiXR Tablet & Droplet Icon
Tris ADHD LiquiXR Technology Logo
Our medications are different because they use drug delivery technology that combines fast-acting and long-lasting medication all-in-one. Our liquid and tablet formulations are designed to release medication gradually over time for ADHD symptom control through the day.1

Explore your ADHD treatment options

Child
Adolescent
Adult
ADHD Child Patient Profile

THE YOUNG ADHD PATIENT

AGE: 6–12 YEARS | GRADE: 1st through 7th

What might this ADHD patient look like?

  • Needs help staying focused for the entire day, including morning, during and after school, and evening when helping out with chores at home
  • Is newly diagnosed with ADHD, has not taken an ADHD medication before, or is currently taking an ADHD medication but may need to switch therapies or add an additional treatment

Which Tris ADHD medication is right for my child?

Only your child's doctor can help you decide which medication is right for your child. This may involve an examination by the doctor, who may ask questions and may perform tests to help with the diagnosis before deciding to prescribe medication.

If you prefer a non-stimulant for your child and are interested in a liquid formulation taken once-nightly, talk to your doctor about ONYDA™ XR (clonidine HCl).

Learn more about ONYDA XR

If your child is starting ADHD medication and prefers the flexibility of a liquid, talk to your doctor about Quillivant XR® (methylphenidate HCl).

Learn more about Quillivant XR

If you and your child's doctor decide that a methylphenidate is right for your child and they prefer a tablet that can be swallowed whole or chewed, talk to your doctor about QuilliChew ER® (methylphenidate HCl).2

Learn more about QuilliChew ER

If your child is ready for an amphetamine medication, and prefers the flexibility of a liquid, talk to your doctor about DYANAVEL® XR (amphetamine) liquid.

Learn more about DYANAVEL XR liquid
ADHD Adolescents Patient Profile

THE ADOLESCENT ADHD PATIENT

AGE: 13 – 17 YEARS | GRADE: 8th through 12th

What might this ADHD patient look like?

  • Needs help staying focused for the entire day, which may include a busy schedule of schoolwork, afterschool activities, a part-time job, chores, and social activities
  • May have taken a methylphenidate ADHD medication before
  • Prefers personalized dosing options in either a tablet or liquid

Which Tris ADHD medication is right for my child?

Only your child's doctor can help you decide which medication is right for your child. This may involve an examination by the doctor, who may ask questions and may perform tests to help with the diagnosis before deciding to prescribe medication.

If you you prefer a non-stimulant for your child and are interested in a liquid formulation taken once-nightly, talk to your doctor about ONYDATM XR (clonidine HCl).

Learn more about ONYDA XR

If you and your child's doctor decide that a methylphenidate is right for your child and they prefer a tablet that can be swallowed whole or chewed, talk to your doctor about QuilliChew ER® (methylphenidate HCl).2

Learn more about QuilliChew ER

If your child is ready for an amphetamine medication, and they prefer a tablet that can be swallowed whole or chewed, talk to your doctor about DYANAVEL® XR (amphetamine) tablet.

Learn more about DYANAVEL XR tablet

THE ADULT ADHD PATIENT

What might this ADHD patient look like?

YOUNG ADULT
AGE: 18 - 24 years
  • Needs help staying focused for the entire day, which may include college, a part-time or first full-time job, and social events
  • Has taken a methylphenidate or amphetamine ADHD medication before
  • Prefers personalized dosing options in either a tablet or liquid
ADULT
AGE: 25+ Years
  • Needs help staying focused for their entire day, which may include long hours, competing priorities, a demanding full-time job, errands, chores, and parenting/caring for family members
  • Has taken a methylphenidate or amphetamine ADHD medication before
  • Prefers personalized dosing options in either a tablet or liquid

Which Tris ADHD medication is right for me?

Only your doctor can help you decide which medication is right for you. This may involve an examination by the doctor, who may ask questions and may perform tests to help with the diagnosis before deciding to prescribe medication.

If you are ready for an amphetamine medication, talk to your doctor about DYANAVEL® XR (amphetamine) tablet.

Learn more about DYANAVEL XR tablet

Choose a savings offer based on the product that your doctor has prescribed*

DYANAVEL XR Tablet
DYANAVEL XR Tablet Savings Card Example
OR
Quillivant XRQuilliChew ER
DYANAVEL XR Liquid
DYANAVEL XR Liquid, Quillivant XR, QuilliChew ER Tris Pharma ADHD Copay Savings Card
OR

* Co-pay offer is subject to eligibility. Terms and Conditions apply.

References: 1. Kando JC, King TR, Pardo A. A novel, modified release drug delivery technology containing amphetamine and methylphenidate ion-exchange complexes. Poster presented at: American Psychiatric Association Annual Meeting; May 1-3, 2021. 2. Abbas R, Childress AC, Nagraj P, Rolke R, Berry SA, Palumbo DR. Relative bioavailability of methylphenidate extended-release chewable tablets chewed versus swallowed whole. Clin Ther. 2018;40(5):733-740.

To report SUSPECTED ADVERSE REACTIONS, contact Tris Pharma, Inc. at (732) 940-0358 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Important Safety Information & Approved Use

DYANAVEL® XR (amphetamine), Quillivant XR® (methylphenidate HCI), and QuilliChew ER® (methylphenidate HCI) are federally controlled substances (CII) because they can be a target for people who abuse prescription medicines or street drugs. DYANAVEL XR, Quillivant XR, and QuilliChew ER have a high chance for abuse and misuse and may lead to substance use problems, including addiction. Keep these medicines in a safe place to prevent abuse and misuse. Selling or giving away these medicines may harm others and is against the law. Your healthcare provider should check you or your child’s risk for abuse, misuse, and addiction before starting treatment with DYANAVEL XR, Quillivant XR, and QuilliChew ER and will monitor you or your child during treatment. Tell your physician if you, your child, or any family members have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

See Additional Important Safety Information.

Important Safety Information & Approved Use


DYANAVEL® XR (amphetamine), Quillivant XR® (methylphenidate HCl), and QuilliChew ER® (methylphenidate HCl) are federally controlled substances (CII) because they can be a target for people who abuse prescription medicines or street drugs. DYANAVEL XR, Quillivant XR, and QuilliChew ER have a high chance for abuse and misuse and may lead to substance use problems, including addiction. Keep these medicines in a safe place to prevent abuse and misuse. Selling or giving away these medicines may harm others and is against the law.

Your healthcare provider should check you or your child’s risk for abuse, misuse, and addiction before starting treatment with DYANAVEL XR, Quillivant XR, and QuilliChew ER and will monitor you or your child during treatment. Tell your physician if you, your child, or any family members have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

DYANAVEL XR, or Quillivant XR and QuilliChew ER, should not be taken if you or your child are allergic to amphetamine or methylphenidate hydrochloride, respectively, or any of the ingredients in these medicines, or are taking or have taken within the past 14 days an anti-depression medicine called a monoamine oxidase inhibitor or MAOI including the antibiotic linezolid and the intravenous medicine methylene blue.

DYANAVEL XR, Quillivant XR, and QuilliChew ER can cause serious side effects. Tell the doctor:

  • if you or your child have heart problems, heart defects, high blood pressure, or a family history of these problems. This is important because sudden death has occurred in children 6 to 17 years old with heart problems or defects, and sudden death, stroke, and heart attack have happened in adults. Your doctor should check you or your child carefully for heart problems before starting any of these medicines. Call the doctor right away if you or your child have any signs of heart problems such as chest pain, shortness of breath, or fainting while taking any of these medicines.
  • Since increases in blood pressure and heart rate may occur, the doctor should regularly check these during treatment.
  • if you or your child have mental problems, or a family history of suicide, bipolar illness, or depression. This is important because new or worsening behavior and thought problems or bipolar illness may occur. New symptoms such as seeing or hearing things that are not real, believing things that are not true, being suspicious, or having new manic symptoms may occur. Call the doctor right away if there are any new or worsening mental symptoms during treatment.
  • if you or your child have circulation problems in fingers and toes (called peripheral vasculopathy, including Raynaud’s phenomenon). Fingers or toes may feel numb, cool, painful, sensitive to temperature, and/or change color from pale, to blue, to red. Call the doctor right away if any signs of unexplained wounds appear on fingers or toes while taking DYANAVEL XR, Quillivant XR, or QuilliChew ER.
  • if your child is having slowing of growth (height and weight); Your child should have his or her height and weight checked often while taking DYANAVEL XR, Quillivant XR, or QuilliChew ER.
  • New or worsening tics or worsening Tourette’s syndrome. Tell your healthcare provider if you or your child get any new or worsening tics or worsening Tourette’s syndrome during treatment.
  • There have been cases of increased eye pressure and acute angle closure glaucoma, an emergency that results from a rapid increase in your eye pressure with Quillivant XR and QuilliChew ER. Call your healthcare provider right away if you or your child develop changes in your vision or eye pain, swelling, or redness.
  • if you or your child develop painful and prolonged erections (priapism), seek medical help right away. Priapism has occurred with methylphenidate (Quillivant XR and QuilliChew ER). Because priapism can cause long-lasting damage, it should be checked by a doctor right away.
  • if you or your child have symptoms of serotonin syndrome - agitation, hallucinations, coma, or other changes in mental status; fast heartbeat; sweating or fever; nausea, vomiting, diarrhea; high or low blood pressure; problems controlling movements or muscle twitching; muscle stiffness or tightness. Serotonin syndrome may occur when DYANAVEL XR is taken with certain other medicines and may be life-threatening. Stop DYANAVEL XR and call your doctor or go to the nearest hospital emergency room.
  • if you or your child have phenylketonuria (PKU). QuilliChew ER contains phenylalanine as part of the artificial sweetener, aspartame. The artificial sweetener may be harmful to people with PKU or who are allergic to phenylalanine.
  • if you or your child are pregnant or plan to become pregnant. It is not known if DYANAVEL XR, Quillivant XR, or QuilliChew ER will harm your unborn baby. There is a pregnancy registry for females who are exposed to DYANAVEL XR, Quillivant XR, or QuilliChew ER during pregnancy. The purpose of the registry is to collect information about the health of females exposed to DYANAVEL XR, Quillivant XR, or QuilliChew ER and their baby. If you or your child becomes pregnant during treatment with DYANAVEL XR, Quillivant XR, or QuilliChew ER, talk to your healthcare provider about registering with the National Pregnancy Registry for Psychostimulants at 1-866-961-2388 or visit https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/othermedications/.
  • You and your child should not breastfeed while you are taking DYANAVEL XR. You and your healthcare provider should decide if you will take Quillivant XR or QuilliChew ER or breastfeed.

Common side effects of amphetamine products include:

  • dry mouth
  • nausea
  • extreme mood changes
  • decreased appetite
  • trouble sleeping
  • dizziness
  • weight loss
  • restlessness
  • increased heart rate
  • stomach pain

Common side effects of methylphenidate products inlude:

  • decreased appetite
  • stomach pain
  • irritability
  • trouble sleeping
  • weight loss
  • mood swings
  • nausea
  • anxiety
  • fast heart beat
  • vomiting
  • dizziness
  • increased blood pressure
  • indigestion

Talk to your doctor if you or your child have any side effects that bother you or do not go away.

Avoid drinking alcohol while taking DYANAVEL XR, Quillivant XR, or QuilliChew ER.

To report SUSPECTED ADVERSE REACTIONS, contact Tris Pharma, Inc. at (732) 940-0358 or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

APPROVED USE

DYANAVEL XR, Quillivant XR, and QuilliChew ER are central nervous system (CNS) stimulant prescription medicines used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in people 6 years and older. These medicines may help increase attention and decrease impulsiveness and hyperactivity in people with ADHD.

It is not known if DYANAVEL XR, Quillivant XR, and QuilliChew ER are safe and effective in children under 6 years of age.

See Medication Guide for DYANAVEL XR, Quillivant XR, and QuilliChew ER.

See Full Prescribing Information for DYANAVEL XR, Quillivant XR, and QuilliChew ER, including Boxed Warning about Abuse, Misuse and Addiction.

APPROVED USE


ONYDA™ XR (clonidine HCI) is a prescription medicine used for the treatment of attention deficit hyperactivity disorder (ADHD) alone or with certain other ADHD medicines in children 6 years of age and older.

It is not known if ONYDA XR is safe and effective in children under 6 years of age.

IMPORTANT SAFETY INFORMATION

Who should not take ONYDA XR?

  • Do not take ONYDA XR if you are allergic to clonidine.

ONYDA XR can cause serious side effects, including:

  • Allergic reactions. You may develop an allergic reaction to ONYDA XR if you had an allergic reaction to clonidine taken through your skin in a patch. Stop taking ONYDA XR and call your healthcare provider right away or go to the nearest emergency room if you develop any signs or symptoms of an allergic reaction, including:
    • skin rash
    • hives
    • swelling of the eyes, face, lips, or tongue
  • Decreased blood pressure and heart rate. ONYDA XR can decrease your blood pressure and heart rate, which can increase your chance of passing out (syncope). If you have a history of passing out or have other medical problems as mentioned above, your risk is higher. Your healthcare provider should check your heart rate and blood pressure before starting treatment and regularly during treatment with ONYDA XR. Do not become dehydrated or too hot (overheated) to decrease your chance of passing out during treatment with ONYDA XR. Before taking ONYDA XR, tell your healthcare provider about all of your medical conditions, including if you: have kidney problems; have low or high blood pressure; have heart problems, including slow heart rate or other heart-rhythm problems; had a stroke or have stroke symptoms.
  • Sleepiness and tiredness that could cause slow reaction times (sedation and somnolence). Do not drive, operate heavy machinery, or do other dangerous activities until you know how ONYDA XR affects you because ONYDA XR can cause sleepiness and tiredness that could cause slow reaction times. Do not drink alcohol or take other medicines that make you sleepy or dizzy during treatment with ONYDA XR until you talk with your healthcare provider.
  • Rebound high blood pressure (hypertension). Suddenly stopping ONYDA XR can cause high blood pressure to return if you have a history of high blood pressure. Suddenly stopping ONYDA XR may also cause withdrawal symptoms including headache, increased heart rate, nausea, flushing or warm feeling, lightheadedness, tightness in your chest, and nervousness or anxiety. Do not suddenly stop ONYDA XR treatment without first talking to your healthcare provider.

The most common side effects of ONYDA XR when used alone include:

  • falling asleep or sleepiness and tiredness that could cause slow reaction times
  • irritability
  • nightmares
  • trouble sleeping
  • constipation
  • dry mouth

The most common side effects of ONYDA XR when used with other ADHD medicines include:

  • falling asleep or sleepiness and tiredness that could cause slow reaction times
  • decreased appetite
  • dizziness

ONYDA XR may cause fertility problems in females and males, which may affect your ability to have a child. Talk to your healthcare provider if this is a concern for you.

These are not all of the possible side effects of ONYDA XR. Call your doctor for medical advice about side effects.

ONYDA XR and certain other medicines may affect each other, causing serious side effects. Especially tell your healthcare provider if you take:

  • antidepression medicines
  • heart or blood pressure medicines
  • other medicines for ADHD
  • other medicines that contain clonidine
  • medicines that cause sleepiness (sedation)

Ask your healthcare provider or pharmacist if you are not sure if your medicine is listed above.

Know the medicines that you take. Keep a list of your medicines with you to show your healthcare provider and pharmacist when you get a new medicine.

Before taking ONYDA XR, tell your healthcare provider, if you:

  • Are pregnant or plan to become pregnant. It is not known if ONYDA XR will harm the unborn baby.

    There is a pregnancy registry for females who are exposed to ADHD medications, including ONYDA XR, during pregnancy. The purpose of the registry is to collect information about the health of females exposed to ONYDA XR and their baby. If you become pregnant during treatment with ONYDA XR, talk to your healthcare provider about registering with the National Pregnancy Registry of ADHD Medications at 1-866-961-2388 or visit online at https://womensmentalhealth.org/adhdmedications/
  • Are breastfeeding or plan to breastfeed. ONYDA XR passes into the breast milk. Babies who are breastfed during treatment with ONYDA XR may become very sleepy, develop relaxed or floppy muscles, and develop trouble breathing. Call the baby’s healthcare provider if the baby is breastfed during treatment with ONYDA XR and develops any of these symptoms. Talk to your healthcare provider about the best way to feed your baby if you take ONYDA XR.

To report side effects, contact Tris Pharma, Inc. at 1-732-940-0358 or the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.

Please see ONYDA XR Full Prescribing information and Patient Information, including Instructions for Use.

How can we help?

Use our contact form to get answers or request more information on any of the Tris Pharma family of ADHD medications.

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