Quillivant XR is the first once-daily, extended-release liquid methylphenidate used for the treatment of ADHD. Quillivant XR is a central nervous system stimulant prescription liquid medicine that is taken by mouth once in the morning, with or without food. Quillivant XR may help increase attention and decrease impulsiveness and hyperactivity in people with ADHD. It is not known if Quillivant XR is safe and effective in children under 6 years of age.
Quillivant XR may be used as part of a treatment program for ADHD that may include counseling or other therapies.
The “XR” stands for “eXtended Release.”
Quillivant XR contains methylphenidate that uses technology to allow for a continuous release of medication throughout the day. This means that Quillivant XR only needs to be taken once each day in the morning.
In a clinical study performed in a laboratory classroom, Quillivant XR was given once daily in the morning for 4 to 6 weeks, where the right dose was identified for each patient, and after remaining for 1 week on that dose. At the end of the 1-week period each child's attention and behavior were measured. Quillivant XR was found effective at reducing the symptoms of ADHD in children ages 6-12 years at all measured times (45 minutes; 2, 4, 8, 10, and 12 hours after taking) compared to a sugar syrup.
The effectiveness of Quillivant XR was assessed in a laboratory classroom study. Teachers and raters used a rating scale (SKAMP) to evaluate the efficacy of Quillivant XR on attention and behavior in children with ADHD ages 6-12 years. Quillivant XR was demonstrated to work at 45 minutes and keep working for 12 hours after taking. In a clinical study performed in a laboratory classroom, Quillivant XR was found effective at reducing the symptoms of ADHD in children ages 6-12 years at all measured times (45 minutes; 2, 4, 8, 10, and 12 hours after taking) compared to a sugar syrup.
The most common side effects reported were mood swings, skin scratching, lack of sleep, involuntary rapid movement or speech, decreased appetite, vomiting, motion sickness, eye pain, and rash
Based on accumulated data from other methylphenidate products, the most common (≥5% and twice the rate of placebo) adverse reactions are appetite decreased, insomnia, nausea, vomiting, dyspepsia, abdominal pain, weight decreased, anxiety, dizziness, irritability, affect lability, tachycardia, and blood pressure increased.
Quillivant XR is banana-flavored.
Store Quillivant XR in a safe place at 59°F to 86°F (15°C to 30°C). Keep Quillivant XR and all medicines out of the reach of children.
Quillivant XR comes as a powder that your pharmacist will mix for you into a liquid. Depending on the prescription from your doctor, you will be given 1 or 2 bottles (containing the liquid form of Quillivant XR), with the bottle adapter already fully inserted by the pharmacist. You will also be given 1 oral dosing dispenser. Please refer to the Instructions for Use for a full description of each item.
Take Quillivant XR exactly as prescribed by your doctor and as instructed by your pharmacist. Quillivant XR is taken once each day in the morning.
Quillivant XR was demonstrated to start working 45 minutes after taking. In a clinical study performed in a laboratory classroom, Quillivant XR was found effective at reducing the symptoms of ADHD in children ages 6-12 years at all measured times (45 minutes; 2, 4, 8, 10, and 12 hours after taking) compared to a sugar syrup.
Quillivant XR works in 45 minutes and keeps working for 12 hours after taking. That means that when taken at 7 am, Quillivant XR may be effective through evening. In a clinical study performed in a laboratory classroom, Quillivant XR was found effective at reducing the symptoms of ADHD in children ages 6-12 years at all measured times (45 minutes; 2, 4, 8, 10, and 12 hours after taking) compared to a sugar syrup.
Quillivant XR is a federally controlled substance (CII) because it can be abused or lead to dependence. Keep Quillivant XR in a safe place to prevent misuse and abuse. Selling or giving away Quillivant XR may harm others, and is against the law. Tell your healthcare provider if you or your child have (or have a family history of) ever abused or been dependent on alcohol, prescription medicines, or street drugs.